E-Pharmacies are slowly acquiring a major stake in the overall pharmacy retail value chain in India. India’s e-pharmacy market is seen growing at speedy pace due to surging internet, mobile phone penetration, and Government-led initiatives. The e-pharmacy market was valued at $344.78 Million in 2021 and is expected to witness robust growth of 21.28% to 2027. During pandemic times, the Central and State Government understood the need of E-Pharmacies and classified them as an essential service and also promoted them on the Aarogya Setu App. The Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP), Digital India, Ayushman Bharat, Startup India and National Digital Health Mission (NDHM) are some of the initiatives undertaken by the Government to boost the growth and enhance the ease of doing business in the online pharmacy segment.